Enhancing Macromolecule Characterization: Trustworthy Insights with the Optima™ AUC System
Beckman Coulter introduced the first AUC sample characterization instrument to help the scientific community power new discoveries. That tradition continues into the 21st century with the new Optima™ AUC system. This latest tool is the most robust technology for providing data used to determine protein molecular weight in basic protein research and quantification of aggregation levels for academic and biopharmaceutical research.
AUC is referred to as an orthogonal method to characterize exosomes, AAV, viral vectors, and virus load characterization.
Optima™ AUC
Enables characterization of samples in their native state
A specialized ultracentrifuge with unique detection capabilities
Monitors a wide variety of particles
No standards required: relies on first principles of thermodynamics
Want to learn more about Analytical Ultracentrifugation? Take a more in-depth look at our AUC Resources Section.
Multiple orthogonal techniques in one instrument
The Optima AUC is a versatile tool for your lab with the ability to use:
Sedimentation Velocity (SV)
Density Gradient Equilibrium (DGE)
Analytical Band Centrifugation (ABC)
Sedimentation Equilibrium (SE)
Each of these operate based on different principles and provide complementary information. With the Optima AUC, you have the flexibility to choose experiment type(s) based on the answer you need. For example, an AAV workflow could include DGE for rapid, high-throughput quantification of particle fullness for in-process samples and SV could be used for attaining the highest resolution answers, including aggregation, necessary for final lot release.
You can use the same hardware across experiments, so think of the Optima AUC as your all-in-one separations toolbox.
Our products
Optima AUC Analytical Ultracentrifuge package with Absorbance and Interference optics, Starter Kit (1 Counter balance, 1 Torque stand, 1 Quartz cell, 1 accessory kit) and 1 AN-50 rotor.
Beckman Coulter introduced the first AUC sample characterization instrument to help the scientific community power new discoveries. That tradition continues into the 21st century with the new Optima™ AUC system.
This latest tool is the most robust technology for providing data used to determine protein molecular weight in basic protein research and quantification of aggregation levels for academic and biopharma research.
Want to learn more about Analytical Ultracentrifugation? Take a more in-depth look at our AUC Resources Section.
Features :
Improved Data Quality
Higher radial resolution
Better signal to noise ratio than ProteomeLab
11x more vertical pixels for interference optics
Enables precise analysis of complex systems at discrete wavelengths (up to 20) in minimal time
Analyzes a wide array of particles in native, matrix-free conditions, including:
Proteins, Nanoparticles, Peptides, Polymers, Micelles, Liposomes, Extracellular vesicles, Drug conjugates, Viral payload
Provides data which can answer more critical questions than any other comparable technique, including:
Shape, Mass, Diameter, Stoichiometry, Heterogeneity, Association, Aggregation, Purity, Formulation
Easier to Use
User-friendly touchscreen display indicates intuitive progression of experimental design.
Remote monitoring capabilities let you set up, monitor and extract data from virtually any location.
Compatibility with ProteomeLab XL cells and rotors
Toggle optics expedite workflow preparation.
This vacuum grease is for o-ring lubrification. Lubrification will protect the o-ring and maintain efficiency of the closure systems.
946-mL bottles of Solution 555™ Rotor Cleaning Concentrate, minimum order 2 bottles.
Beckman Solution 555 (339555) is a mild and efficient detergent that won’t damage the rotors.
Under normal use, as part of the day-to-day care and maintenance program, wash the rotor frequently to prevent the buildup of residues.