Blood grouping reagent for the detection of the K (Kell) antigen on human red cells
Pelikloon anti-K (IgM) monoclonal blood grouping reagent (clone number is mentioned on the corresponding certificate of analysis/release document and product label) are prepared from culture supernatants from stable hybridoma cell lines as first described by Köhler and Milstein (Nature 1975). This monoclonal reagent contain human IgM antibodies and has been specially selected and developed to provide a reliable alternative to polyclonal reagents. This reagent meets the requirements of the concerned standards and guidelines. Performance characteristics are mentioned in the release documents, which are supplied with the product upon request. The principle of the test is the agglutination technique, which is based on antigen/antibody reaction. The reagent can be used in either spin tube or microplate method. This reagent is also suitable for use in automated test systems and should be standardised and validated by the user. The inclusion of positive and negative controls with each series of blood group determinations is strongly recommended.