Harvesting Tangential Flow Filtration (TFF)

Cell (or biomass) harvesting, or clarification of supernatant, are important processes in nearly all downstream purifications of biotech-based products.
When the product is internal to the cells, cell harvesting is used to decrease the liquid volume of cells to be processed in the product extraction steps.
Available methods for cell harvesting include TFF (Tangential Flow Filtration) and the combination of Centrifugation with depth filtration.