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PHARMA & BIOTECH RESEARCH

FIGHTING COVID-19 TOGETHER

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VACCINE DEVELOPMENT


 
CELL CULTURE & FERMENTATION
The control system of the Memmert CO2 incubator ICOmed is so finely tuned that the appliance reaches the setpoint temperature very quickly and without temperature overshoots.
Ultimate-Cell stackable shaking incubator is the comprehensive solution with temperature, shaking speed, and optional features, e.g. CO2, humidity controls.  
Article: MIGAL researchers claimed in early March 2020 to be able to develop an oral vaccine for testing in 3 months due to the similar DNA structure with the current IBV vaccine. To simplify production, MIGAL turned to Solaris to provide its most modern Jupiter bioreactors.        
 BROCHURE

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PORTFOLIO OVERVIEW

 
HARVESTING & PURIFICATION
TFF Systems can scale from bench top to pilot and industrial scale applications. Includes state of the art components integration and controlling technology.

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LIQUID HANDLING & AUTOMATION
Start your experiments with success thanks to the manual liquid handling portfolio from HTL.
  • Automated Liquid Handling - Beckman Coulter

    • The Beckman automation platforms are there to assist you in every step of your vaccine development process, whether you are in development, needing to construct numerous antibodies, or using cell lines within your process, automation can help you to achieve more in less time. If you need to run ELISA experiments further in your development process, we have the skills and support team to assist you.
    • Cell line development - Development of stable or transient cell lines for the production of purified antigens can be automated using 21 CFR Part 11-supported Biomek i-Series automated liquid handlers.
    • Antibody construction - Synthetic antibody construction by miniaturizing isothermal DNA assembly is enabled thanks to the Echo 525.
    • Antibody Engineering - Antibody engineering using hybridoma based technology to make antibodies and evaluate their specificity with ELISA using an end-to-end Biomek i-Series-based system.

  • Liquid handling calibration & verification systems - Artel


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MONITORING, CONTROL & CHARACTERIZATION
Test samples quickly, easily and accurately—keeping your test cell cultures in balance, viable and growing. Watch the video
Simple Life Cell Imaging system to stay safe & save time by not having to enter the laboratory and get dressed. See note
Automated, Easy, Quick, Reliable. Discover The new Vi-CELL BLU: Watch the video
Coulter Counter Multisizer 4E counts and measures every single particle and change in size in a measuring solution (including cells, bacteria or microparticles). 
Study of the immunity mechanisms with the adaptative flow cytometer BECKMAN COULTER CytoFlex and a ready-to-use cocktail DURACLONE.
Watch the video - Brochure - Article
Get fast, accurate results for gene therapies and oligonucleotides.

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VIRUS QUANTIFICATION & FORMULATION

Particle characterization

The BECKMAN COULTER LS measures particles in nearly any suspension as well as particles dispersed in air. Measurement range of 10 nm - 3500 µm. Dry Powder System (400 nm - 3500 µm). Universal Liquid module (10 nm-2000 µm). Already used for the production and quantification of (dry powder) vaccines (influenza and norovirus)
Article 1  -  Article 2

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CANDIDATE SCREENING & FORMULATION

 
CLINICAL TESTING
Study of the immunity mechanisms with the adaptative flow cytometer BECKMAN COULTER CytoFlex and a ready-to-use cocktail DURACLONE.
Watch the video        Brochure
Article: Cossarizza, A., De Biasi, S., Guaraldi, G., Girardis, M., Mussini, C. and (2020), SARS‐CoV‐2, the Virus that Causes COVID‐19: Cytometry and the New Challenge for Global Health. Cytometry, 97: 340-343. doi:10.1002/cyto.a.24002

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VACCINES COLD STORAGE SOLUTIONS

In the coming weeks, the biggest challenge with regard to COVID-19  will be the preservation of the cold vaccine supply chain.
Everyone knows that any failure in this chain would be disastrous for the effectiveness of the vaccines. Thanks to its large equipment range, Analis provides complete and integrated solutions for :

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