Air Monitoring & Cleanroom Monitoring
Analis has air monitoring and cleanrom monitoring solutions for all your biological targets.
Single aspirating head air sampler with Bluetooth cable for charging and HEPA Filter:
TRIO.BAS™ MONO FILTER
HEPA FILTER MOUNTED ON AIR SAMPLERThe active viable air samplers for viable contamination monitoring in Cleanroom / Isolator / RABS should not pose a contamination risk during their use.
In this case, to avoid this risk of transfer of particles from the inside part of instrument aspirating chamber, it is suggested to adopt a HEPA filter fixed on the air outlet of instrument for an easy control or on the satellite units of stainless steel family of samplers. The purpose of the filter is to stop the potential transfer of particles.
The HEPA filter is externally positioned and therefore the replacement is very simple.
Microbioal Environmental Monitoring: ORUM TrioBas Solutions
There are many types of microbial air samplers. The most used one is the microbial air sampler based on the impact method on an agar plate (also known as impactor). This type of sampler has 2 main components: an air pump and a head piece. The head piece contains an agar plate. The air pump pulls the air through a perforated cover into the headpiece. The air then makes a short turn above the agar plate. Due to the centrifugal force, the particles in the air make contact with the agar surface and they stick. Micro-organisms always travel on dust or aerosol particles. They rarely travel on their own. By incubating the agar plate after the sampling, the micro-organisms will multiply. After a certain incubation time, the clusters of bacteria are visible on the plate, and the so called colony forming units can be counted. Based on the volume of sampled air, you can then calculate the number of colony forming units present per volume of air. This method is the most used for the so called ‘active air sampling’ or ‘viable particle monitoring’.
What are the advantages of a microbial air sampler by impact on agar?
This method has a large advantage when you do routine microbial quality control of the air. The most common used parameters for this are total viable count, and total yeasts and moulds. Usually, you have an idea of the range of colony forming units in the air, and you only want to measure cultivable micro-organisms. Using the microbial air sampler by impact on agar you have a very fast, easy, and cheap method to monitor the air quality. You sample directly on the plate, incubate, and count it. Culturing is the most easy and cheap detection method. It is widely used in different industries and guidelines.
What does the EU GMP Annex 1 say about air monitoring?
The EU GMP Annex 1 is a guideline for the sterile production (in pharma and biotech production environments). The EU GMP Annex 1 has a section that talks about ‘Viable and non-viable environmental & process monitoring’. Air monitoring is a big part of this section. The guideline talks about 3 types of air monitoring:
- Passive sampling of viable particles/ settle plates: this is a simulation of the reality. You open the agar plate for max 4 hours, you close it, incubate it, and at the end you can count the colonies.
- Volumetric air sampling / active air sampling of viable particles: this is most often done with an impactor/ microbial air sampler. You sample max 1000L per plate. After that, you incubate the plate, and you count the colonies. This gives you exact data about the number of viable particles per volume of air.
- Monitoring of non-viable particle: for this part, you measure the number of dust particles of <0,5 µm and <5µm using an air sampling instrument (often referred to as particle counters).
TRIO.BAS MONO 100 Petri PACK with Cable
Item No. 337416
ORUM INTERNATIONAL S.R.L. 212K Microbial air samplers
TRIO.BAS MONO FILTER 100 Petri PACK with Cable
Item No. 337631
ORUM INTERNATIONAL S.R.L. 170K Microbial air samplers
TRIO.BAS MONO ATEX 100 Petri PACK
Item No. 337648
ORUM INTERNATIONAL S.R.L. 208K Microbial air samplers
TRIO.BAS DUO 100 Petri PACK with Cable
Item No. 337652
ORUM INTERNATIONAL S.R.L. 223K Microbial air samplers
TRIO.BAS DUO ATEX 100 Petri PACK
Item No. 337667
ORUM INTERNATIONAL S.R.L. 246K Microbial air samplers
TRIO.GAS with ASPI GAS Petri PACK
Item No. 337694
ORUM INTERNATIONAL S.R.L. 653K Microbial air samplers