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Cellbind Screen

Item No. 324227
Micro column test for the detection or identification of red cell antibodies as well as for blood grouping The Cellbind Screen assay is a micro column test system in which sensitised red cells from a suspension are caught by a gel matrix containing anti-IgG, anti-IgM, and anti-C3d in an enhancing
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Description
Micro column test for the detection or identification of red cell antibodies as well as for blood grouping

The Cellbind Screen assay is a micro column test system in which sensitised red cells from a suspension are caught by a gel matrix containing anti-IgG, anti-IgM, and anti-C3d in an enhancing high-density medium. Each screen card consists of six micro columns containing the gel in the high-density medium. Cellbind Screen is intended for use in the detection or identification of red cell antibodies, as well as for blood grouping, crossmatching and the modified direct antiglobulin test (DAT, for the detection of in vivo coating of red cells with antibodies and complement components). Cellbind Screen is suitable for use in manual as well as (semi-) automated systems. The Cellbind Screen assay meets the requirements of the concerned standards and guidelines. Performance characteristics are mentioned in the release documents, which are supplied with the product upon request. The test is based on the immunofixation of sensitised red cells in a micro column containing a gel matrix. The cell suspension is added to the incubation compartment of the micro column, together with the plasma, serum or blood grouping reagent to be tested. During the incubation phase antigen-positive red cells will bind the corresponding anti-red cell antibodies present in the plasma, serum or reagent. Next, the cards are subjected to three phases of centrifugation. In the first phase the high-density medium will cause separation of the red cells from the plasma, serum or reagent. In the second phase sensitised red cells will be agglutinated and caught on top of the gel matrix in the micro column, while in the third phase non-sensitised and very weakly sensitised red cells will move towards the bottom of the micro column. The inclusion of positive and negative controls with each series of blood group determinations is strongly recommended.
Specifications
Brand SANQUIN REAGENTS B.V.
External reference K7000
Storage conditions 2. Store between 2°C and 8°C
Transport conditions 6. Refrigerated Standard
Product Group Immuno-hematology Reagent
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