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CCC coombs control cells

Item No. 324171
3% Cell suspensions for the control of the antiglobulin test The reagent red cells are suspended in a special preservation medium. These reagents meet the requirements of the concerned standards and guidelines. Performance characteristics are mentioned in the release documents, which are supplied
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Description
3% Cell suspensions for the control of the antiglobulin test

The reagent red cells are suspended in a special preservation medium. These reagents meet the requirements of the concerned standards and guidelines. Performance characteristics are mentioned in the release documents, which are supplied with the product upon request. The principle of the test is the agglutination technique, which is based on antigen/antibody reaction. Reliable results from the (in)direct antiglobulin test in blood group serology are essential. As a result of inadequate washing procedures, serum proteins (IgG) which are still present may neutralise the antiglobulin serum and thus inhibit agglutination. To detect this and other causes of neutralised antiglobulin reagent, Coombs Control Cells should be added to every test tube yielding a negative result. Coombs Control Cells are prepared in accordance with an optimal procedure developed by Sanquin. Coombs Control Cells and Coombs Control Cells strong are IgG sensitised Group O Rhesus D-positive human red cells that have been sensitised in vitro with different amounts of anti-D (IgG) antibodies. Coombs Control Cells strong are manufactured to produce strong agglutination in the presence of active antiglobulin reagents. Coombs Control Cells are prepared to produce less strong agglutination in the presence of active antiglobulin reagents. Coombs Control Cells moderately sensitised with IgG provide a more sensitive and reliable indication of (partial) neutralisation of the antiglobulin reagents. The Coombs Control Cells are washed and resuspended in a special preservation medium and can be added directly to the test tubes.
Specifications
Brand SANQUIN REAGENTS B.V.
External reference K1145
Storage conditions 2. Store between 2°C and 8°C
Transport conditions 6. Refrigerated Standard
Product Group Immuno-hematology Controls
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